There are several over-the-counter spot treatments that can be effective in treating acne. It’s important to keep in mind that what works for one person may not work for another, so it may be necessary to try a few different products to find what works best for you.

Here are some options for spot treatments for acne:

1. Salicylic acid: This is a type of beta hydroxy acid that helps to exfoliate the skin and unclog pores. It is available in a variety of products, including gels, creams, and pads.
2. Benzoyl peroxide: This is a powerful antimicrobial agent that can kill the bacteria that cause acne. It is available in a variety of concentrations and can be found in creams, gels, and spot treatments.
3. Sulfur: This is a natural antimicrobial agent that can help to reduce inflammation and unclog pores. It is often found in spot treatments and cleansers.
4. Tea tree oil: This is a natural antimicrobial agent that can help to kill acne-causing bacteria and reduce inflammation. It is available in a variety of products, including spot treatments, cleansers, and toners.
5. Niacinamide: This is a type of vitamin B3 that has anti-inflammatory and antioxidant properties. It is available in a variety of products, including creams and serums, and can help to reduce the appearance of acne and improve skin texture.

It’s important to remember to use these products only on the affected areas, as overuse or improper use of these products can cause irritation or dryness. It’s also a good idea to speak with a dermatologist if you are experiencing persistent or severe acne, as they can provide more specialised treatment options.